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Stage specific requirement of platelet-derived growth factor receptor-α in embryonic development
BACKGROUND: Platelet-derived growth factor receptor alpha (PDGFRα) is a cell-surface receptor tyrosine kinase for platelet-derived growth factors. Correct timing and level of Pdgfra expression is crucial for embryo development, and deletion of Pdgfra caused developmental defects of multiple endoderm...
Autores principales: | Qian, Chen, Wong, Carol Wing Yan, Wu, Zhongluan, He, Qiuming, Xia, Huimin, Tam, Paul Kwong Hang, Wong, Kenneth Kak Yuen, Lui, Vincent Chi Hang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608218/ https://www.ncbi.nlm.nih.gov/pubmed/28934221 http://dx.doi.org/10.1371/journal.pone.0184473 |
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