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Oncolytic potency and reduced virus tumor-specificity in oncolytic virotherapy. A mathematical modelling approach
In the present paper, we address by means of mathematical modeling the following main question: How can oncolytic virus infection of some normal cells in the vicinity of tumor cells enhance oncolytic virotherapy? We formulate a mathematical model describing the interactions between the oncolytic vir...
Autores principales: | Mahasa, Khaphetsi Joseph, Eladdadi, Amina, de Pillis, Lisette, Ouifki, Rachid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608221/ https://www.ncbi.nlm.nih.gov/pubmed/28934210 http://dx.doi.org/10.1371/journal.pone.0184347 |
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