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Vps35-deficiency impairs SLC4A11 trafficking and promotes corneal dystrophy

Vps35 (vacuolar protein sorting 35) is a major component of retromer that selectively promotes endosome-to-Golgi retrieval of transmembrane proteins. Dysfunction of retromer is a risk factor for the pathogenesis of Parkinson’s disease (PD) and Alzheimer’s disease (AD). However, Vps35/retromer’s func...

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Detalles Bibliográficos
Autores principales:	Liu, Wei, Tang, Fu-Lei, Lin, Sen, Zhao, Kai, Mei, Lin, Ye, Jian, Xiong, Wen-Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608277/ https://www.ncbi.nlm.nih.gov/pubmed/28934248 http://dx.doi.org/10.1371/journal.pone.0184906

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