Patient-derived osteosarcoma cells are resistant to methotrexate

Osteosarcoma is the most common primary bone tumor in children and young adults. The median survival of osteosarcoma patients has not significantly improved since 1990, despite administration of different classes of chemotherapy agents, such as methotrexate, cisplatin and doxorubicin. Cancer stem ce...

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Detalles Bibliográficos
Autores principales: dos Santos Cavalcanti, Amanda, Meohas, Walter, Ribeiro, Gabriele de Oliveira, de Sá Lopes, Ana Cristina, Gholamin, Sharareh, Razavi, Mostafa, Hanae Kasai Brunswick, Taís, Avan, Amir, Matheus Guimarães, João Antonio, Leite Duarte, Maria Eugenia, Kahn, Suzana Assad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608286/
https://www.ncbi.nlm.nih.gov/pubmed/28934267
http://dx.doi.org/10.1371/journal.pone.0184891

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