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A map of protein dynamics during cell-cycle progression and cell-cycle exit

The cell-cycle field has identified the core regulators that drive the cell cycle, but we do not have a clear map of the dynamics of these regulators during cell-cycle progression versus cell-cycle exit. Here we use single-cell time-lapse microscopy of Cyclin-Dependent Kinase 2 (CDK2) activity follo...

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Detalles Bibliográficos
Autores principales: Gookin, Sara, Min, Mingwei, Phadke, Harsha, Chung, Mingyu, Moser, Justin, Miller, Iain, Carter, Dylan, Spencer, Sabrina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608403/
https://www.ncbi.nlm.nih.gov/pubmed/28892491
http://dx.doi.org/10.1371/journal.pbio.2003268