Retinitis Pigmentosa Associated with Glucose-6-Phosphate Dehydrogenase Deficiency

We report a case of new onset retinitis pigmentosa (RP) associated with a glucose-6-phosphate dehydrogenase (G6PD) deficiency in a 63-year-old African-American male who presented with worsening night vision over a period of five years. The pathogenesis of G6PD-mediated oxidative biological damage is...

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Detalles Bibliográficos
Autores principales: Thiel, Bryan, Sharma, Aman, Shaikh, Saad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2017
Materias:
Ophthalmology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608491/
https://www.ncbi.nlm.nih.gov/pubmed/28948126
http://dx.doi.org/10.7759/cureus.1506
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author Thiel, Bryan
Sharma, Aman
Shaikh, Saad
author_facet Thiel, Bryan
Sharma, Aman
Shaikh, Saad
author_sort Thiel, Bryan
collection PubMed
description We report a case of new onset retinitis pigmentosa (RP) associated with a glucose-6-phosphate dehydrogenase (G6PD) deficiency in a 63-year-old African-American male who presented with worsening night vision over a period of five years. The pathogenesis of G6PD-mediated oxidative biological damage is reviewed and a mechanism for the onset of retinal disease proposed. 
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spelling pubmed-56084912017-09-25 Retinitis Pigmentosa Associated with Glucose-6-Phosphate Dehydrogenase Deficiency Thiel, Bryan Sharma, Aman Shaikh, Saad Cureus Ophthalmology We report a case of new onset retinitis pigmentosa (RP) associated with a glucose-6-phosphate dehydrogenase (G6PD) deficiency in a 63-year-old African-American male who presented with worsening night vision over a period of five years. The pathogenesis of G6PD-mediated oxidative biological damage is reviewed and a mechanism for the onset of retinal disease proposed.  Cureus 2017-07-23 /pmc/articles/PMC5608491/ /pubmed/28948126 http://dx.doi.org/10.7759/cureus.1506 Text en Copyright © 2017, Thiel et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Ophthalmology
Thiel, Bryan
Sharma, Aman
Shaikh, Saad
Retinitis Pigmentosa Associated with Glucose-6-Phosphate Dehydrogenase Deficiency
title Retinitis Pigmentosa Associated with Glucose-6-Phosphate Dehydrogenase Deficiency
title_full Retinitis Pigmentosa Associated with Glucose-6-Phosphate Dehydrogenase Deficiency
title_fullStr Retinitis Pigmentosa Associated with Glucose-6-Phosphate Dehydrogenase Deficiency
title_full_unstemmed Retinitis Pigmentosa Associated with Glucose-6-Phosphate Dehydrogenase Deficiency
title_short Retinitis Pigmentosa Associated with Glucose-6-Phosphate Dehydrogenase Deficiency
title_sort retinitis pigmentosa associated with glucose-6-phosphate dehydrogenase deficiency
topic Ophthalmology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608491/
https://www.ncbi.nlm.nih.gov/pubmed/28948126
http://dx.doi.org/10.7759/cureus.1506
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AT sharmaaman retinitispigmentosaassociatedwithglucose6phosphatedehydrogenasedeficiency
AT shaikhsaad retinitispigmentosaassociatedwithglucose6phosphatedehydrogenasedeficiency

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