Distinct stages of synapse elimination are induced by burst firing of CA1 neurons and differentially require MEF2A/D

Experience and activity refine cortical circuits through synapse elimination, but little is known about the activity patterns and downstream molecular mechanisms that mediate this process. We used optogenetics to drive individual mouse CA1 hippocampal neurons to fire in theta frequency bursts to und...

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Detalles Bibliográficos
Autores principales: Chang, Chia-Wei, Wilkerson, Julia R, Hale, Carly F, Gibson, Jay R, Huber, Kimberly M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608508/
https://www.ncbi.nlm.nih.gov/pubmed/28901289
http://dx.doi.org/10.7554/eLife.26278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608508/
https://www.ncbi.nlm.nih.gov/pubmed/28901289
http://dx.doi.org/10.7554/eLife.26278

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