Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins

Ubiquilins (Ubqlns) are a family of ubiquitin receptors that promote the delivery of hydrophobic and aggregated ubiquitinated proteins to the proteasome for degradation. We carried out a proteomic analysis of a B cell lymphoma-derived cell line, BJAB, that requires UBQLN1 for survival to identify UB...

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Detalles Bibliográficos
Autores principales: Whiteley, Alexandra M, Prado, Miguel A, Peng, Ivan, Abbas, Alexander R, Haley, Benjamin, Paulo, Joao A, Reichelt, Mike, Katakam, Anand, Sagolla, Meredith, Modrusan, Zora, Lee, Dong Yun, Roose-Girma, Merone, Kirkpatrick, Donald S, McKenzie, Brent S, Gygi, Steven P, Finley, Daniel, Brown, Eric J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608509/
https://www.ncbi.nlm.nih.gov/pubmed/28933694
http://dx.doi.org/10.7554/eLife.26435

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