Cargando…
Impact of siponimod on vaccination response in a randomized, placebo-controlled study
OBJECTIVE: To evaluate effects of siponimod on response to T-cell–dependent (influenza) and T-cell–independent (pneumococcal polysaccharide vaccine [PPV-23]) vaccinations in healthy participants. METHODS: In this double-blind, placebo-controlled, parallel-group study, each participant underwent a 7-...
Autores principales: | Ufer, Mike, Shakeri-Nejad, Kasra, Gardin, Anne, Su, Zhenzhong, Paule, Ines, Marbury, Thomas C., Legangneux, Eric |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608565/ https://www.ncbi.nlm.nih.gov/pubmed/28955715 http://dx.doi.org/10.1212/NXI.0000000000000398 |
Ejemplares similares
-
Effect of Fluconazole Coadministration and CYP2C9 Genetic Polymorphism on Siponimod Pharmacokinetics in Healthy Subjects
por: Gardin, Anne, et al.
Publicado: (2018) -
In vitro studies and in silico predictions of fluconazole and CYP2C9 genetic polymorphism impact on siponimod metabolism and pharmacokinetics
por: Jin, Yi, et al.
Publicado: (2017) -
Abuse and dependence potential of sphingosine-1-phosphate (S1P) receptor modulators used in the treatment of multiple sclerosis: a review of literature and public data
por: Schoedel, Kerri A., et al.
Publicado: (2021) -
Siponimod (BAF312) penetrates, distributes, and acts in the central nervous system: Preclinical insights
por: Bigaud, Marc, et al.
Publicado: (2021) -
Siponimod for multiple sclerosis
Publicado: (2021)