Lunatic Fringe and p53 Cooperatively Suppress Mesenchymal Stem-Like Breast Cancer

Claudin-low breast cancer (CLBC) is a poor prognosis molecular subtype showing stemness and mesenchymal features. We previously discovered that deletion of a Notch signaling modulator, Lunatic Fringe (Lfng), in the mouse mammary gland induced a subset of tumors resembling CLBC. Here we report that d...

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Detalles Bibliográficos
Autores principales: Chung, Wen-Cheng, Zhang, Shubing, Challagundla, Lavanya, Zhou, Yunyun, Xu, Keli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608590/
https://www.ncbi.nlm.nih.gov/pubmed/28938159
http://dx.doi.org/10.1016/j.neo.2017.08.006

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