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Tetanus immunity status among adult trauma patients in an ED

OBJECTIVES: Tetanus is a vaccine-preventable infectious disease. It is caused by the bacterium Clostridium tetani. The aim of this study was to investigate tetanus immunity among adult trauma patients. MATERIAL AND METHODS: This study was performed with 267 trauma patients who were admitted to the e...

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Autores principales: Toker, Ibrahim, Kılıc, Turgay Yılmaz, Kose, Sukran, Yesilaras, Murat, Calıskan, Feriyde, Atilla, Ozge Duman, Unek, Orkun, Hacar, Serkan, Kılınc Toker, Aysin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608600/
https://www.ncbi.nlm.nih.gov/pubmed/28971156
http://dx.doi.org/10.1016/j.tjem.2017.02.001
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author Toker, Ibrahim
Kılıc, Turgay Yılmaz
Kose, Sukran
Yesilaras, Murat
Calıskan, Feriyde
Atilla, Ozge Duman
Unek, Orkun
Hacar, Serkan
Kılınc Toker, Aysin
author_facet Toker, Ibrahim
Kılıc, Turgay Yılmaz
Kose, Sukran
Yesilaras, Murat
Calıskan, Feriyde
Atilla, Ozge Duman
Unek, Orkun
Hacar, Serkan
Kılınc Toker, Aysin
author_sort Toker, Ibrahim
collection PubMed
description OBJECTIVES: Tetanus is a vaccine-preventable infectious disease. It is caused by the bacterium Clostridium tetani. The aim of this study was to investigate tetanus immunity among adult trauma patients. MATERIAL AND METHODS: This study was performed with 267 trauma patients who were admitted to the emergency department of Tepecik Training and Research Hospital in Izmir City, Turkey over a six month period. After obtaining a written informed consent from each patient, a questionnaire concerning demographic information and tetanus vaccination history was filled in by the physician. Patients' blood samples (4–5 cc) were drawn into a test tube while creating an intravenous (IV) access prior to making any attempt for therapy. And the tetanus antibody level (IgG) was measured using the enzyme-linked immunosorbent assay method. Tetanus antibody levels ≥0.1 IU/mL were considered protective. RESULTS: Among 267 patients, 192 and 75 of the cases (71.9% and 28.1%) were male and female, respectively. The median age of the patients was 39 (IQRs = 28–52). Seventy-five percent of the patients (n = 201) had protective immunity rates for tetanus. DISCUSSION AND CONCLUSION: In our study, which was conducted among adults, it was found that the protective ratio of tetanus immunity decreased with age with an additional, significant decline in elderly patients.
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spelling pubmed-56086002017-10-02 Tetanus immunity status among adult trauma patients in an ED Toker, Ibrahim Kılıc, Turgay Yılmaz Kose, Sukran Yesilaras, Murat Calıskan, Feriyde Atilla, Ozge Duman Unek, Orkun Hacar, Serkan Kılınc Toker, Aysin Turk J Emerg Med Original Article OBJECTIVES: Tetanus is a vaccine-preventable infectious disease. It is caused by the bacterium Clostridium tetani. The aim of this study was to investigate tetanus immunity among adult trauma patients. MATERIAL AND METHODS: This study was performed with 267 trauma patients who were admitted to the emergency department of Tepecik Training and Research Hospital in Izmir City, Turkey over a six month period. After obtaining a written informed consent from each patient, a questionnaire concerning demographic information and tetanus vaccination history was filled in by the physician. Patients' blood samples (4–5 cc) were drawn into a test tube while creating an intravenous (IV) access prior to making any attempt for therapy. And the tetanus antibody level (IgG) was measured using the enzyme-linked immunosorbent assay method. Tetanus antibody levels ≥0.1 IU/mL were considered protective. RESULTS: Among 267 patients, 192 and 75 of the cases (71.9% and 28.1%) were male and female, respectively. The median age of the patients was 39 (IQRs = 28–52). Seventy-five percent of the patients (n = 201) had protective immunity rates for tetanus. DISCUSSION AND CONCLUSION: In our study, which was conducted among adults, it was found that the protective ratio of tetanus immunity decreased with age with an additional, significant decline in elderly patients. Elsevier 2017-02-20 /pmc/articles/PMC5608600/ /pubmed/28971156 http://dx.doi.org/10.1016/j.tjem.2017.02.001 Text en © 2017 The Emergency Medicine Association of Turkey. Production and hosting by Elsevier B.V. on behalf of the Owner. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Toker, Ibrahim
Kılıc, Turgay Yılmaz
Kose, Sukran
Yesilaras, Murat
Calıskan, Feriyde
Atilla, Ozge Duman
Unek, Orkun
Hacar, Serkan
Kılınc Toker, Aysin
Tetanus immunity status among adult trauma patients in an ED
title Tetanus immunity status among adult trauma patients in an ED
title_full Tetanus immunity status among adult trauma patients in an ED
title_fullStr Tetanus immunity status among adult trauma patients in an ED
title_full_unstemmed Tetanus immunity status among adult trauma patients in an ED
title_short Tetanus immunity status among adult trauma patients in an ED
title_sort tetanus immunity status among adult trauma patients in an ed
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608600/
https://www.ncbi.nlm.nih.gov/pubmed/28971156
http://dx.doi.org/10.1016/j.tjem.2017.02.001
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