Neuregulin-2 ablation results in dopamine dysregulation and severe behavioral phenotypes relevant to psychiatric disorders

Numerous genetic and functional studies implicate variants of Neuregulin-1 (NRG1) and its neuronal receptor ErbB4 in schizophrenia and many of its endophenotypes. Although the neurophysiological and behavioral phenotypes of NRG1 mutant mice have been investigated extensively, practically nothing is...

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Detalles Bibliográficos
Autores principales: Yan, L, Shamir, A, Skirzewski, M, Leiva-Salcedo, E, Kwon, O B, Karavanova, I, Paredes, D, Malkesman, O, Bailey, K R, Vullhorst, D, Crawley, J N, Buonanno, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608621/
https://www.ncbi.nlm.nih.gov/pubmed/28322273
http://dx.doi.org/10.1038/mp.2017.22

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