Combined activation of MAP kinase pathway and β-catenin signaling cause deep penetrating nevi

Deep penetrating nevus (DPN) is characterized by enlarged, pigmented melanocytes that extend through the dermis. DPN can be difficult to distinguish from melanoma but rarely displays aggressive biological behavior. Here, we identify a combination of mutations of the β-catenin and mitogen-activated p...

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Detalles Bibliográficos
Autores principales: Yeh, Iwei, Lang, Ursula E., Durieux, Emeline, Tee, Meng Kian, Jorapur, Aparna, Shain, A. Hunter, Haddad, Veronique, Pissaloux, Daniel, Chen, Xu, Cerroni, Lorenzo, Judson, Robert L., LeBoit, Philip E., McCalmont, Timothy H., Bastian, Boris C., de la Fouchardière, Arnaud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608693/
https://www.ncbi.nlm.nih.gov/pubmed/28935960
http://dx.doi.org/10.1038/s41467-017-00758-3

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