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Hyponatremia and V2 vasopressin receptor upregulation: a result of HSP90 inhibition
PURPOSE: Small-molecule inhibitors of heat-shock protein 90 (HSP90) have been under development as chemotherapeutic agents. The adverse events reported from early clinical trials included hyponatremia. Given the limited number of patients enrolled, the number of hyponatremia incidents was remarkable...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608778/ https://www.ncbi.nlm.nih.gov/pubmed/28779264 http://dx.doi.org/10.1007/s00280-017-3390-x |