Absolute quantitation of disease protein biomarkers in a single LC-MS acquisition using apolipoprotein F as an example

LC-MS and immunoassay can detect protein biomarkers. Immunoassays are more commonly used but can potentially be outperformed by LC-MS. These techniques have limitations including the necessity to generate separate calibration curves for each biomarker. We present a rapid mass spectrometry-based assa...

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Detalles Bibliográficos
Autores principales: Kumar, Abhinav, Gangadharan, Bevin, Cobbold, Jeremy, Thursz, Mark, Zitzmann, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608892/
https://www.ncbi.nlm.nih.gov/pubmed/28935895
http://dx.doi.org/10.1038/s41598-017-12229-2

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