Split dosing of artemisinins does not improve antimalarial therapeutic efficacy

It has been suggested recently, based on pharmacokinetic-pharmacodynamic modelling exercises, that twice daily dosing of artemisinins increases malaria parasite killing and so could “dramatically enhance and restore drug effectiveness” in artemisinin resistant P. falciparum malaria infections. It wa...

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Detalles Bibliográficos
Autores principales: White, N. J., Watson, J., Ashley, E. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608907/
https://www.ncbi.nlm.nih.gov/pubmed/28935919
http://dx.doi.org/10.1038/s41598-017-12483-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608907/
https://www.ncbi.nlm.nih.gov/pubmed/28935919
http://dx.doi.org/10.1038/s41598-017-12483-4

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