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Split dosing of artemisinins does not improve antimalarial therapeutic efficacy
It has been suggested recently, based on pharmacokinetic-pharmacodynamic modelling exercises, that twice daily dosing of artemisinins increases malaria parasite killing and so could “dramatically enhance and restore drug effectiveness” in artemisinin resistant P. falciparum malaria infections. It wa...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608907/ https://www.ncbi.nlm.nih.gov/pubmed/28935919 http://dx.doi.org/10.1038/s41598-017-12483-4 |