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Endoplasmic reticulum stress signaling and chemotherapy resistance in solid cancers
The unfolded protein response (UPR) is an adaptive cellular program used by eukaryotic cells to cope with protein misfolding stress. During tumor development, cancer cells are facing intrinsic (oncogene activation) and extrinsic (limiting nutrient or oxygen supply) challenges, with which they must c...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608920/ https://www.ncbi.nlm.nih.gov/pubmed/28846078 http://dx.doi.org/10.1038/oncsis.2017.72 |