Deoxyribonuclease 1 reduces pathogenic effects of cigarette smoke exposure in the lung

Our aim was to investigate if deoxyribonuclease (DNase) 1 is a potential therapeutic agent to reduce pathogenic effects of cigarette smoke exposure in the lung. Cigarette smoke causes protease imbalance with excess production of proteases, which is a key process in the pathogenesis of emphysema. The...

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Detalles Bibliográficos
Autores principales: King, Paul T., Sharma, Roleen, O’Sullivan, Kim M., Callaghan, Judy, Dousha, Lovisa, Thomas, Belinda, Ruwanpura, Saleela, Lim, Steven, Farmer, Michael W., Jennings, Barton R., Finsterbusch, Michaela, Brooks, Gavin, Selemidis, Stavros, Anderson, Gary P., Holdsworth, Stephen R., Bardin, Philip G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608940/
https://www.ncbi.nlm.nih.gov/pubmed/28935869
http://dx.doi.org/10.1038/s41598-017-12474-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608940/
https://www.ncbi.nlm.nih.gov/pubmed/28935869
http://dx.doi.org/10.1038/s41598-017-12474-5

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