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Indoleamine 2,3-dioxygenase and inducible nitric oxide synthase mediate immune tolerance induced by CTLA4Ig and anti-CD154 hematopoietic stem cell transplantation in a sensitized mouse model

Cytotoxic T-lymphocyte-associated protein 4 immunoglobulin (CTLA4Ig) and anti-cluster of differentiation 154 (anti-CD154) are able to block B7/CD28 and CD40/CD154 co-stimulatory signals in T cells. Additionally, they promote hematopoietic stem cell transplantation (HSCT) in sensitized recipients and...

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Detalles Bibliográficos
Autores principales: Ye, Qi-Xiang, Xu, Lv-Hong, Shi, Pei-Jie, Xia, Ting, Fang, Jian-Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609130/
https://www.ncbi.nlm.nih.gov/pubmed/28962099
http://dx.doi.org/10.3892/etm.2017.4722