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A simple and traceless solid phase method simplifies the assembly of large peptides and the access to challenging proteins
Chemical protein synthesis gives access to well-defined native or modified proteins that are useful for studying protein structure and function. The majority of proteins synthesized up to now have been produced using native chemical ligation (NCL) in solution. Although there are significant advantag...
Autores principales: | Ollivier, N., Desmet, R., Drobecq, H., Blanpain, A., Boll, E., Leclercq, B., Mougel, A., Vicogne, J., Melnyk, O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609153/ https://www.ncbi.nlm.nih.gov/pubmed/28970915 http://dx.doi.org/10.1039/c7sc01912b |
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