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Smad7-overexpressing rat BMSCs inhibit the fibrosis of hepatic stellate cells by regulating the TGF-β1/Smad signaling pathway
Mesenchymal stem cells (MSCs) are able to differentiate into hepatocytes, promote the regeneration of hepatic cells and inhibit the progression of hepatic fibrosis. Transforming growth factor (TGF)-β1 is one of the key factors in the development of liver fibrosis, which also promotes extracellular m...
Autores principales: | Wu, Shi-Pin, Yang, Zhi, Li, Fu-Rong, Liu, Xiao-Di, Chen, Hong-Tao, Su, Dong-Na |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609222/ https://www.ncbi.nlm.nih.gov/pubmed/28962196 http://dx.doi.org/10.3892/etm.2017.4836 |
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