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Tumour‐targeting bacteria‐based cancer therapies for increased specificity and improved outcome

‘You have cancer’ – a devastating diagnosis that still strikes patients hard. Despite substantial improvements of standard therapies over the years, there is still no general cure available. Here, we review the revival of an old concept – the use of bacteria as cancer therapeutics. Bacteria‐mediated...

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Detalles Bibliográficos
Autores principales: Felgner, Sebastian, Pawar, Vinay, Kocijancic, Dino, Erhardt, Marc, Weiss, Siegfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609243/
https://www.ncbi.nlm.nih.gov/pubmed/28771926
http://dx.doi.org/10.1111/1751-7915.12787
Descripción
Sumario:‘You have cancer’ – a devastating diagnosis that still strikes patients hard. Despite substantial improvements of standard therapies over the years, there is still no general cure available. Here, we review the revival of an old concept – the use of bacteria as cancer therapeutics. Bacteria‐mediated tumor therapy has great potential to evolve into a powerful tool against malignant solid tumors.