Biscarbamate Cross-Linked Low-Molecular-Weight Polyethylenimine for Delivering Anti-chordin siRNA into Human Mesenchymal Stem Cells for Improving Bone Regeneration

Small-interfering RNA (siRNA) provides a rapid solution for drug design and provides new methods to develop customizable medicines. Polyethyleneimine 25 kDa (PEI25kDa) is an effective transfection agent used in siRNA delivery. However, the lack of degradable linkage causes undesirable toxicity, hind...

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Detalles Bibliográficos
Autores principales: Wang, Chuandong, Yuan, Weien, Xiao, Fei, Gan, Yaokai, Zhao, Xiaotian, Zhai, Zhanjing, Zhao, Xiaoying, Zhao, Chen, Cui, Penglei, Jin, Tuo, Chen, Xiaodong, Zhang, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609535/
https://www.ncbi.nlm.nih.gov/pubmed/28970797
http://dx.doi.org/10.3389/fphar.2017.00572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609535/
https://www.ncbi.nlm.nih.gov/pubmed/28970797
http://dx.doi.org/10.3389/fphar.2017.00572

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