Critical role of β1 integrin in postnatal beta-cell function and expansion

β1 integrin is essential for pancreatic beta-cell development and maintenance in rodents and humans. However, the effects of a temporal beta-cell specific β1 integrin knockout on adult islet function are unknown. We utilized a mouse insulin 1 promoter driven tamoxifen-inducible Cre-recombinase β1 in...

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Detalles Bibliográficos
Autores principales: Peart, Jason, Li, Jinming, Lee, Hojun, Riopel, Matthew, Feng, Zhi-Chao, Wang, Rennian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609893/
https://www.ncbi.nlm.nih.gov/pubmed/28968961
http://dx.doi.org/10.18632/oncotarget.17969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609893/
https://www.ncbi.nlm.nih.gov/pubmed/28968961
http://dx.doi.org/10.18632/oncotarget.17969

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