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BMI-1 is a potential therapeutic target in diffuse intrinsic pontine glioma

Diffuse intrinsic pontine glioma (DIPG) is a poor-prognosis pediatric brain tumor. No effective curative therapy is currently available and no therapeutic advances have been made in several decades. BMI-1 is a member of the multimeric protein complex Polycomb repressor complex 1. It is highly expres...

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Detalles Bibliográficos
Autores principales: Kumar, Shiva Senthil, Sengupta, Satarupa, Lee, Kyungwoo, Hura, Nanki, Fuller, Christine, DeWire, Mariko, Stevenson, Charles B., Fouladi, Maryam, Drissi, Rachid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609895/
https://www.ncbi.nlm.nih.gov/pubmed/28968963
http://dx.doi.org/10.18632/oncotarget.18002