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Preclinical testing of the glycogen synthase kinase-3β inhibitor tideglusib for rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is the most common childhood soft tissue sarcoma. RMS often arise from myogenic precursors and displays a poorly differentiated skeletal muscle phenotype most closely resembling regenerating muscle. GSK3β is a ubiquitously expressed serine-threonine kinase capable of repressin...

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Detalles Bibliográficos
Autores principales: Bharathy, Narendra, Svalina, Matthew N., Settelmeyer, Teagan P., Cleary, Megan M., Berlow, Noah E., Airhart, Susan D., Xiang, Sunny, Keck, James, Hayden, James B., Shern, Jack F., Mansoor, Atiya, Lathara, Melvin, Srinivasa, Ganapati, Langenau, David M., Keller, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609896/
https://www.ncbi.nlm.nih.gov/pubmed/28968964
http://dx.doi.org/10.18632/oncotarget.18520