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Preclinical testing of the glycogen synthase kinase-3β inhibitor tideglusib for rhabdomyosarcoma
Rhabdomyosarcoma (RMS) is the most common childhood soft tissue sarcoma. RMS often arise from myogenic precursors and displays a poorly differentiated skeletal muscle phenotype most closely resembling regenerating muscle. GSK3β is a ubiquitously expressed serine-threonine kinase capable of repressin...
Autores principales: | Bharathy, Narendra, Svalina, Matthew N., Settelmeyer, Teagan P., Cleary, Megan M., Berlow, Noah E., Airhart, Susan D., Xiang, Sunny, Keck, James, Hayden, James B., Shern, Jack F., Mansoor, Atiya, Lathara, Melvin, Srinivasa, Ganapati, Langenau, David M., Keller, Charles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609896/ https://www.ncbi.nlm.nih.gov/pubmed/28968964 http://dx.doi.org/10.18632/oncotarget.18520 |
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