Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer

Diversity in colorectal cancer biology is associated with variable responses to standard chemotherapy. We aimed to identify and validate DNA hypermethylated genes as predictive biomarkers for irinotecan treatment of metastatic CRC patients. Candidate genes were selected from 389 genes involved in DN...

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Detalles Bibliográficos
Autores principales: Bosch, Linda J.W., Trooskens, Geert, Snaebjornsson, Petur, Coupé, Veerle M.H., Mongera, Sandra, Haan, Josien C., Richman, Susan D., Koopman, Miriam, Tol, Jolien, de Meyer, Tim, Louwagie, Joost, Dehaspe, Luc, van Grieken, Nicole C.T., Ylstra, Bauke, Verheul, Henk M.W., van Engeland, Manon, Nagtegaal, Iris D., Herman, James G., Quirke, Philip, Seymour, Matthew T., Punt, Cornelis J.A., van Criekinge, Wim, Carvalho, Beatriz, Meijer, Gerrit A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609910/
https://www.ncbi.nlm.nih.gov/pubmed/28968978
http://dx.doi.org/10.18632/oncotarget.18702

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