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HMGB1 promotes myeloid-derived suppressor cells and renal cell carcinoma immune escape

Despite high immunogenicity and marked presence of immune cells in the RCC(renal cell carcinoma), immunotherapy fails to develop effective anti-tumor immune responses. This is due to the negative regulatory factors in the tumor microenvironment. As the main contributor of immunosuppression, myeloid-...

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Detalles Bibliográficos
Autores principales: Li, Jinfeng, Sun, Jiajia, Rong, Ruiming, Li, Long, Shang, Wenjun, Song, Dongkui, Feng, Guiwen, Luo, Feifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609921/
https://www.ncbi.nlm.nih.gov/pubmed/28968989
http://dx.doi.org/10.18632/oncotarget.18796