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HMGB1 promotes myeloid-derived suppressor cells and renal cell carcinoma immune escape
Despite high immunogenicity and marked presence of immune cells in the RCC(renal cell carcinoma), immunotherapy fails to develop effective anti-tumor immune responses. This is due to the negative regulatory factors in the tumor microenvironment. As the main contributor of immunosuppression, myeloid-...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609921/ https://www.ncbi.nlm.nih.gov/pubmed/28968989 http://dx.doi.org/10.18632/oncotarget.18796 |