APC/C is essential for hematopoiesis and impaired in aplastic anemia

Anaphase promoting complex/cyclosome (APC/C) is essential for cell cycle progression. Recently, its non-mitotic functions were also reported but less studied in several tissues including hematopoietic cells. Here, we developed an inducible Anapc2 (a core subunit of APC/C) knockout mice. The animals...

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Detalles Bibliográficos
Autores principales: Wang, Jia, Yin, Min-Zhi, Zhao, Ke-Wen, Ke, Fang, Jin, Wen-Jie, Guo, Xiao-Lin, Liu, Tian-Hui, Liu, Xiao-Ye, Gu, Hao, Yu, Xiao-Min, Li, Zhen, Mu, Li-Li, Hong, Deng-Li, Chen, Jing, Chen, Guo-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609928/
https://www.ncbi.nlm.nih.gov/pubmed/28968996
http://dx.doi.org/10.18632/oncotarget.18808

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