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Arginine auxotrophic gene signature in paediatric sarcomas and brain tumours provides a viable target for arginine depletion therapies

Paediatric sarcomas and brain tumours, remain cancers of significant unmet need, with a poor prognosis for patients with high risk disease or those who relapse, and significant morbidities from treatment for those that survive using standard treatment approaches. Novel treatment strategies, based on...

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Detalles Bibliográficos
Autores principales:	Vardon, Ashley, Dandapani, Madhumita, Cheng, Daryl, Cheng, Paul, De Santo, Carmela, Mussai, Francis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609939/ https://www.ncbi.nlm.nih.gov/pubmed/28969007 http://dx.doi.org/10.18632/oncotarget.18843

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