Increasing UCP2 expression and decreasing NOX1/4 expression maintain chondrocyte phenotype by reducing reactive oxygen species production

The aim of this study is to demonstrate that improving the mitochondrial function can inhibite the loss of chondrocyte phenotype by regulating the expression of uncoupling protein 2(UCP2) and NADPH oxidase1/4(NOX1/4) to reduce the production of reactive oxygen species(ROS). The effects of mitochondr...

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Detalles Bibliográficos
Autores principales: Miao, Yansong, Dong, Yuefu, Huang, Ping, Zhao, Xiang, Huang, Zhenyu, Yao, Jufang, Li, He, Xu, Qingrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609958/
https://www.ncbi.nlm.nih.gov/pubmed/28969026
http://dx.doi.org/10.18632/oncotarget.18908

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