Gene methylation biomarkers in sputum as a classifier for lung cancer risk

CT screening for lung cancer reduces mortality, but will cost Medicare ∼2 billion dollars due in part to high false positive rates. Molecular biomarkers could augment current risk stratification used to select smokers for screening. Gene methylation in sputum reflects lung field cancerization that r...

Descripción completa

Detalles Bibliográficos
Autores principales: Leng, Shuguang, Wu, Guodong, Klinge, Donna M., Thomas, Cynthia L., Casas, Elia, Picchi, Maria A., Stidley, Christine A., Lee, Sandra J., Aisner, Seena, Siegfried, Jill M., Ramalingam, Suresh, Khuri, Fadlo R., Karp, Daniel D., Belinsky, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609978/
https://www.ncbi.nlm.nih.gov/pubmed/28969046
http://dx.doi.org/10.18632/oncotarget.19255

Ejemplares similares

Ejemplares similares