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Aberrant DNA methylation of GATA binding protein 3 (GATA3), interleukin-4 (IL-4), and transforming growth factor-β (TGF-β) promoters in Behcet's disease

The pathogenesis of Behcet's disease (BD) remains poorly understood. The purpose of this study was to investigate whether an aberrant DNA methylation of transcriptional and inflammatory factors, including TBX21, GATA3, RORγt, FOXP3, IFN-γ, IL-4, IL-17A and TGF-β, in CD4(+)T confers risk to BD....

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Detalles Bibliográficos
Autores principales: Zhu, Yunyun, Qiu, Yiguo, Yu, Hongsong, Yi, Shenglan, Su, Wencheng, Kijlstra, Aize, Yang, Peizeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610000/
https://www.ncbi.nlm.nih.gov/pubmed/28969068
http://dx.doi.org/10.18632/oncotarget.19500