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Aberrant DNA methylation of GATA binding protein 3 (GATA3), interleukin-4 (IL-4), and transforming growth factor-β (TGF-β) promoters in Behcet's disease
The pathogenesis of Behcet's disease (BD) remains poorly understood. The purpose of this study was to investigate whether an aberrant DNA methylation of transcriptional and inflammatory factors, including TBX21, GATA3, RORγt, FOXP3, IFN-γ, IL-4, IL-17A and TGF-β, in CD4(+)T confers risk to BD....
Autores principales: | Zhu, Yunyun, Qiu, Yiguo, Yu, Hongsong, Yi, Shenglan, Su, Wencheng, Kijlstra, Aize, Yang, Peizeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610000/ https://www.ncbi.nlm.nih.gov/pubmed/28969068 http://dx.doi.org/10.18632/oncotarget.19500 |
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