Integrated metabolic models for xenobiotic induced mitochondrial toxicity in skeletal muscle

There is a need for robust in vitro models to sensitively capture skeletal muscle adverse toxicities early in the research and development of novel xenobiotics. To this end, an in vitro rat skeletal muscle model (L6) was used to study the translation of transcriptomics data generated from an in vivo...

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Detalles Bibliográficos
Autores principales: Dott, William, Wright, Jayne, Cain, Kelvin, Mistry, Pratibha, Herbert, Karl E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610037/
https://www.ncbi.nlm.nih.gov/pubmed/28942197
http://dx.doi.org/10.1016/j.redox.2017.09.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610037/
https://www.ncbi.nlm.nih.gov/pubmed/28942197
http://dx.doi.org/10.1016/j.redox.2017.09.006

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