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A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage

Zika virus infection during pregnancy can cause congenital abnormities or fetal demise. The persistence of Zika virus in the male reproductive system poses a risk of sexual transmission. Here we demonstrate that live-attenuated Zika virus vaccine candidates containing deletions in the 3′ untranslate...

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Detalles Bibliográficos
Autores principales: Shan, Chao, Muruato, Antonio E., Jagger, Brett W., Richner, Justin, Nunes, Bruno T. D., Medeiros, Daniele B. A., Xie, Xuping, Nunes, Jannyce G. C., Morabito, Kaitlyn M., Kong, Wing-Pui, Pierson, Theodore C., Barrett, Alan D., Weaver, Scott C., Rossi, Shannan L., Vasconcelos, Pedro F. C., Graham, Barney S., Diamond, Michael S., Shi, Pei-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610254/
https://www.ncbi.nlm.nih.gov/pubmed/28939807
http://dx.doi.org/10.1038/s41467-017-00737-8