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FLT1 and transcriptome-wide polyadenylation site (PAS) analysis in preeclampsia

Maternal symptoms of preeclampsia (PE) are primarily driven by excess anti-angiogenic factors originating from the placenta. Chief among these are soluble Flt1 proteins (sFlt1s) produced from alternatively polyadenylated mRNA isoforms. Here we used polyadenylation site sequencing (PAS-Seq) of RNA fr...

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Detalles Bibliográficos
Autores principales:	Ashar-Patel, Ami, Kaymaz, Yasin, Rajakumar, Augustine, Bailey, Jeffrey A., Karumanchi, S. Ananth, Moore, Melissa J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610261/ https://www.ncbi.nlm.nih.gov/pubmed/28939845 http://dx.doi.org/10.1038/s41598-017-11639-6

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