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Differential Proteomics Identifies Reticulocalbin-3 as a Novel Negative Mediator of Collagen Production in Human Cardiac Fibroblasts

Cardiac fibrosis is characterized by an excessive accumulation of extracellular matrix components, including collagens. Galectin-3 (Gal-3) and Cardiotrophin-1 (CT-1) are two profibrotic molecules that mediate Aldosterone (Aldo)-induced cardiac fibrosis. However the underlying mechanisms are not well...

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Detalles Bibliográficos
Autores principales:	Martínez-Martínez, Ernesto, Ibarrola, Jaime, Fernández-Celis, Amaya, Santamaria, Enrique, Fernández-Irigoyen, Joaquín, Rossignol, Patrick, Jaisser, Frederic, López-Andrés, Natalia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610303/ https://www.ncbi.nlm.nih.gov/pubmed/28939891 http://dx.doi.org/10.1038/s41598-017-12305-7

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