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Brain Inflammation, Blood Brain Barrier dysfunction and Neuronal Synaptophysin Decrease after Inhalation Exposure to Titanium Dioxide Nano-aerosol in Aging Rats

Notwithstanding potential neurotoxicity of inhaled titanium dioxide nanoparticles (TiO(2) NPs), the toxicokinetics and consequences on blood-brain barrier (BBB) function remain poorly characterized. To improve risk assessment, we need to evaluate the impact on BBB under realistic environmental condi...

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Detalles Bibliográficos
Autores principales:	Disdier, Clémence, Chalansonnet, Monique, Gagnaire, François, Gaté, Laurent, Cosnier, Frédéric, Devoy, Jérôme, Saba, Wadad, Lund, Amie K., Brun, Emilie, Mabondzo, Aloïse
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610323/ https://www.ncbi.nlm.nih.gov/pubmed/28939873 http://dx.doi.org/10.1038/s41598-017-12404-5

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