miR-155 mediates arsenic trioxide resistance by activating Nrf2 and suppressing apoptosis in lung cancer cells

Arsenic trioxide (ATO) resistance is a challenging problem in chemotherapy. However, the underlying mechanisms remain to be elucidated. In this study, we identified a high level of expression of miR-155 in a human lung adenocarcinoma A549R cell line that is highly resistant to ATO. We showed that th...

Descripción completa

Detalles Bibliográficos
Autores principales: Gu, Shiyan, Lai, Yanhao, Chen, Hongyu, Liu, Yuan, Zhang, Zunzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610328/
https://www.ncbi.nlm.nih.gov/pubmed/28939896
http://dx.doi.org/10.1038/s41598-017-06061-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610328/
https://www.ncbi.nlm.nih.gov/pubmed/28939896
http://dx.doi.org/10.1038/s41598-017-06061-x

Ejemplares similares