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miR-155 mediates arsenic trioxide resistance by activating Nrf2 and suppressing apoptosis in lung cancer cells

Arsenic trioxide (ATO) resistance is a challenging problem in chemotherapy. However, the underlying mechanisms remain to be elucidated. In this study, we identified a high level of expression of miR-155 in a human lung adenocarcinoma A549R cell line that is highly resistant to ATO. We showed that th...

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Detalles Bibliográficos
Autores principales:	Gu, Shiyan, Lai, Yanhao, Chen, Hongyu, Liu, Yuan, Zhang, Zunzhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610328/ https://www.ncbi.nlm.nih.gov/pubmed/28939896 http://dx.doi.org/10.1038/s41598-017-06061-x

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