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Determination of extracellular matrix collagen fibril architectures and pathological remodeling by polarization dependent second harmonic microscopy
Polarization dependence second harmonic generation (P-SHG) microscopy is gaining increase popularity for in situ quantification of fibrillar protein architectures. In this report, we combine P-SHG microscopy, new linear least square (LLS) fitting and modeling to determine and convert the complex sec...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610346/ https://www.ncbi.nlm.nih.gov/pubmed/28939903 http://dx.doi.org/10.1038/s41598-017-12398-0 |