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Axillary Lymph Node Metastasis in Medullary Thyroid Carcinoma: A Case Report

INTRODUCTION: Medullary thyroid cancer (MTC) is an uncommon neoplasm originating from parafollicular C cells. Distant metastasis in MTC, such as axillary node involvement, is extremely rare. CASE REPORT: The present study describes a known case of MTC with axillary lymph node metastasis in a 31-year...

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Autores principales: Rasihashemi, Seyed Ziaeddin, Azhough, Ramin, Ramouz, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610379/
https://www.ncbi.nlm.nih.gov/pubmed/28955678
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author Rasihashemi, Seyed Ziaeddin
Azhough, Ramin
Ramouz, Ali
author_facet Rasihashemi, Seyed Ziaeddin
Azhough, Ramin
Ramouz, Ali
author_sort Rasihashemi, Seyed Ziaeddin
collection PubMed
description INTRODUCTION: Medullary thyroid cancer (MTC) is an uncommon neoplasm originating from parafollicular C cells. Distant metastasis in MTC, such as axillary node involvement, is extremely rare. CASE REPORT: The present study describes a known case of MTC with axillary lymph node metastasis in a 31-year-old woman. In 2010, she underwent total thyroidectomy and right-sided modified radical neck dissection. In May 2015, she was referred with a 3-month history of a mass in the left axilla. Fine needle aspiration cytology (FNAC) confirmed MTC in the axillary nodes. Left axillary lymph node dissection was performed and postoperative histopathology revealed metastatic medullary thyroid carcinoma in prepared specimens. CONCLUSION: MTC with axillary lymph node metastasis is a rare condition which has been reported in previous studies to impair patient prognosis. However, in the current case, the patient had no other MTC-related complications subsequent to final lymphadenectomy.
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spelling pubmed-56103792017-09-27 Axillary Lymph Node Metastasis in Medullary Thyroid Carcinoma: A Case Report Rasihashemi, Seyed Ziaeddin Azhough, Ramin Ramouz, Ali Iran J Otorhinolaryngol Case Report INTRODUCTION: Medullary thyroid cancer (MTC) is an uncommon neoplasm originating from parafollicular C cells. Distant metastasis in MTC, such as axillary node involvement, is extremely rare. CASE REPORT: The present study describes a known case of MTC with axillary lymph node metastasis in a 31-year-old woman. In 2010, she underwent total thyroidectomy and right-sided modified radical neck dissection. In May 2015, she was referred with a 3-month history of a mass in the left axilla. Fine needle aspiration cytology (FNAC) confirmed MTC in the axillary nodes. Left axillary lymph node dissection was performed and postoperative histopathology revealed metastatic medullary thyroid carcinoma in prepared specimens. CONCLUSION: MTC with axillary lymph node metastasis is a rare condition which has been reported in previous studies to impair patient prognosis. However, in the current case, the patient had no other MTC-related complications subsequent to final lymphadenectomy. Mashhad University of Medical Sciences 2017-09 /pmc/articles/PMC5610379/ /pubmed/28955678 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Rasihashemi, Seyed Ziaeddin
Azhough, Ramin
Ramouz, Ali
Axillary Lymph Node Metastasis in Medullary Thyroid Carcinoma: A Case Report
title Axillary Lymph Node Metastasis in Medullary Thyroid Carcinoma: A Case Report
title_full Axillary Lymph Node Metastasis in Medullary Thyroid Carcinoma: A Case Report
title_fullStr Axillary Lymph Node Metastasis in Medullary Thyroid Carcinoma: A Case Report
title_full_unstemmed Axillary Lymph Node Metastasis in Medullary Thyroid Carcinoma: A Case Report
title_short Axillary Lymph Node Metastasis in Medullary Thyroid Carcinoma: A Case Report
title_sort axillary lymph node metastasis in medullary thyroid carcinoma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610379/
https://www.ncbi.nlm.nih.gov/pubmed/28955678
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AT ramouzali axillarylymphnodemetastasisinmedullarythyroidcarcinomaacasereport