Re-evaluation of soluble APP-α and APP-β in cerebrospinal fluid as potential biomarkers for early diagnosis of dementia disorders

BACKGROUND: Because soluble (or secreted) amyloid precursor protein-β (sAPPβ) and -α (sAPPα) possibly reflect pathological features of Alzheimer’s disease (AD), they are potential biomarker candidates for dementia disorders, including AD and mild cognitive impairment (MCI) due to AD (MCI-AD). Howeve...

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Detalles Bibliográficos
Autores principales: Araki, Wataru, Hattori, Kotaro, Kanemaru, Kazutomi, Yokoi, Yuma, Omachi, Yoshie, Takano, Harumasa, Sakata, Masuhiro, Yoshida, Sumiko, Tsukamoto, Tadashi, Murata, Miho, Saito, Yuko, Kunugi, Hiroshi, Goto, Yu-ichi, Nagaoka, Utako, Nagao, Masahiro, Komori, Takashi, Arima, Kunimasa, Ishii, Kenji, Murayama, Shigeo, Matsuda, Hiroshi, Tachimori, Hisateru, Araki, Yumiko M., Mizusawa, Hidehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610422/
https://www.ncbi.nlm.nih.gov/pubmed/29018524
http://dx.doi.org/10.1186/s40364-017-0108-5

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