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Intoxication with GHB/GBL: characteristics and trends from ambulance-attended overdoses

BACKGROUND: Overdoses from so-called “club drugs” (GHB/GBL) have become a more frequent cause of overdoses attended by ambulance services. Given its availability, affordability, and lack of awareness of risks, there is a common misconception among users that the drug is relatively safe. METHODS: Thi...

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Autores principales: Madah-Amiri, Desiree, Myrmel, Lars, Brattebø, Guttorm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610436/
https://www.ncbi.nlm.nih.gov/pubmed/28938889
http://dx.doi.org/10.1186/s13049-017-0441-6
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author Madah-Amiri, Desiree
Myrmel, Lars
Brattebø, Guttorm
author_facet Madah-Amiri, Desiree
Myrmel, Lars
Brattebø, Guttorm
author_sort Madah-Amiri, Desiree
collection PubMed
description BACKGROUND: Overdoses from so-called “club drugs” (GHB/GBL) have become a more frequent cause of overdoses attended by ambulance services. Given its availability, affordability, and lack of awareness of risks, there is a common misconception among users that the drug is relatively safe. METHODS: This study reviewed ambulance records in Bergen, Norway between 2009 and 2015 for cases of acute poisonings, particularly from suspected GHB/GBL intoxication. RESULTS: In total, 1112 cases of GHB and GBL poisoning were identified. GHB was suspected for 995 (89%) of the patients. Men made up the majority of the cases (n = 752, 67.6%) with a median age of 27 years old. Temporal trends for GHB/GBL overdoses displayed a late-night, weekend pattern. The most frequent initial symptoms reported were unconsciousness, or reduced consciousness. Most of the patients required further treatment and transport. During the period from 2009 to 2015, there was a nearly 50% decrease in GHB/GBL overdoses from 2013 to 2014. DISCUSSION: The characteristics of GHB/GBL overdose victims shed light on this patient group. The decrease in incidence over the years may be partly due to a legal ban on GBL in Norway, declared in 2010. It may also be due to an increase in the use of MDMA/ecstasy. CONCLUSION: The review of ambulance records on the prehospital treatment of overdoses can be beneficial in monitoring, preparing, and prevention efforts aimed to benefit this vulnerable group.
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spelling pubmed-56104362017-10-10 Intoxication with GHB/GBL: characteristics and trends from ambulance-attended overdoses Madah-Amiri, Desiree Myrmel, Lars Brattebø, Guttorm Scand J Trauma Resusc Emerg Med Original Research BACKGROUND: Overdoses from so-called “club drugs” (GHB/GBL) have become a more frequent cause of overdoses attended by ambulance services. Given its availability, affordability, and lack of awareness of risks, there is a common misconception among users that the drug is relatively safe. METHODS: This study reviewed ambulance records in Bergen, Norway between 2009 and 2015 for cases of acute poisonings, particularly from suspected GHB/GBL intoxication. RESULTS: In total, 1112 cases of GHB and GBL poisoning were identified. GHB was suspected for 995 (89%) of the patients. Men made up the majority of the cases (n = 752, 67.6%) with a median age of 27 years old. Temporal trends for GHB/GBL overdoses displayed a late-night, weekend pattern. The most frequent initial symptoms reported were unconsciousness, or reduced consciousness. Most of the patients required further treatment and transport. During the period from 2009 to 2015, there was a nearly 50% decrease in GHB/GBL overdoses from 2013 to 2014. DISCUSSION: The characteristics of GHB/GBL overdose victims shed light on this patient group. The decrease in incidence over the years may be partly due to a legal ban on GBL in Norway, declared in 2010. It may also be due to an increase in the use of MDMA/ecstasy. CONCLUSION: The review of ambulance records on the prehospital treatment of overdoses can be beneficial in monitoring, preparing, and prevention efforts aimed to benefit this vulnerable group. BioMed Central 2017-09-22 /pmc/articles/PMC5610436/ /pubmed/28938889 http://dx.doi.org/10.1186/s13049-017-0441-6 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Original Research
Madah-Amiri, Desiree
Myrmel, Lars
Brattebø, Guttorm
Intoxication with GHB/GBL: characteristics and trends from ambulance-attended overdoses
title Intoxication with GHB/GBL: characteristics and trends from ambulance-attended overdoses
title_full Intoxication with GHB/GBL: characteristics and trends from ambulance-attended overdoses
title_fullStr Intoxication with GHB/GBL: characteristics and trends from ambulance-attended overdoses
title_full_unstemmed Intoxication with GHB/GBL: characteristics and trends from ambulance-attended overdoses
title_short Intoxication with GHB/GBL: characteristics and trends from ambulance-attended overdoses
title_sort intoxication with ghb/gbl: characteristics and trends from ambulance-attended overdoses
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610436/
https://www.ncbi.nlm.nih.gov/pubmed/28938889
http://dx.doi.org/10.1186/s13049-017-0441-6
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