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Down-regulation of MBD4 contributes to hypomethylation and overexpression of CD70 in CD4(+) T cells in systemic lupus erythematosus

BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by lymphocytic infiltration and overproduction of autoantibodies, leading to significant morbidity and mortality. However, the pathogenesis of this disorder has not yet been completely elucidated. It has be...

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Detalles Bibliográficos
Autores principales:	Liao, Wei, Li, Mengying, Wu, Haijing, Jia, Sujie, Zhang, Nu, Dai, Yong, Zhao, Ming, Lu, Qianjin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610447/ https://www.ncbi.nlm.nih.gov/pubmed/29018507 http://dx.doi.org/10.1186/s13148-017-0405-8

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