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Use of the KlADH3 promoter for the quantitative production of the murine PDE5A isoforms in the yeast Kluyveromyces lactis

BACKGROUND: Phosphodiesterases (PDE) are a superfamily of enzymes that hydrolyse cyclic nucleotides (cAMP/cGMP), signal molecules in transduction pathways regulating crucial aspects of cell life. PDEs regulate the intensity and duration of the cyclic nucleotides signal modulating the downstream biol...

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Detalles Bibliográficos
Autores principales:	Cardarelli, Silvia, Giorgi, Mauro, Naro, Fabio, Malatesta, Francesco, Biagioni, Stefano, Saliola, Michele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610471/ https://www.ncbi.nlm.nih.gov/pubmed/28938916 http://dx.doi.org/10.1186/s12934-017-0779-5

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