Unraveling Drug Penetration of Echinocandin Antifungals at the Site of Infection in an Intra-abdominal Abscess Model

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Intra-abdominal candidiasis (IAC) is a prominent invasive fungal infection associated with high mortality. Prompt antifungal therapy and source control are crucial for successful treatment. Echinocandin antifungal drugs are first-line agents; however, their clinical effectiveness is highly variable,...

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Detalles Bibliográficos
Autores principales: Zhao, Yanan, Prideaux, Brendan, Nagasaki, Yoji, Lee, Min Hee, Chen, Pei-Yu, Blanc, Landry, Ho, Hsinpin, Clancy, Cornelius J., Nguyen, Minh Hong, Dartois, Véronique, Perlin, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610477/
https://www.ncbi.nlm.nih.gov/pubmed/28739797
http://dx.doi.org/10.1128/AAC.01009-17
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